Cardiovascular Effects of Switching From Tobacco Cigarettes to Electronic Cigarettes.

ABSTRACT:

Background

E-cigarette (EC) use is increasing exponentially worldwide. The early cardiovascular effects of switching from tobacco cigarettes (TC) to EC in chronic smokers is unknown. Meta-analysis of flow-mediated dilation (FMD) studies indicate 13% lower pooled, adjusted relative risks of cardiovascular events with every 1% improvement in FMD.

Objectives

This study sought to determine the early vascular impact of switching from TC to EC in chronic smokers.

Methods

The authors conducted a prospective, randomized control trial with a parallel nonrandomized preference cohort and blinded endpoint of smokers ≥18 years of age who had smoked ≥15 cigarettes/day for ≥2 years and were free from established cardiovascular disease. Participants were randomized to EC with nicotin

SUBMITTER: George J 

PROVIDER: S-EPMC6928567 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature