Rapid automated liver quantitative susceptibility mapping.

ABSTRACT:

Background

Accurate measurement of the liver iron concentration (LIC) is needed to guide iron-chelating therapy for patients with transfusional iron overload. In this work, we investigate the feasibility of automated quantitative susceptibility mapping (QSM) to measure the LIC.

Purpose

To develop a rapid, robust, and automated liver QSM for clinical practice.

Study type

Prospective.

Population

13 healthy subjects and 22 patients.

Field strength/sequences

1.5 T and 3 T/3D multiecho gradient-recalled echo (GRE) sequence.

Assessment

Data were acquired using a 3D GRE sequence with an out-of-phase echo spacing with respect to each other. All odd echoes that were in-phase (IP) were used to initialize the fat-water separation and field estimation (T

SUBMITTER: Jafari R 

PROVIDER: S-EPMC6929208 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature