Occupational exposure to formaldehyde and risk of non hodgkin lymphoma: a meta-analysis.

ABSTRACT:

Background

Formaldehyde, a widely used chemical, is considered a human carcinogen. We report the results of a meta-analyses of studies on the relationship between occupational exposure to formaldehyde and risk of non-Hodgkin lymphoma (NHL).

Methods

We performed a systematic review and meta-analysis according to international guidelines and we identified 12 reports of occupational populations exposed to formaldehyde. We evaluated inter-study heterogeneity and we applied a random effects model. We conducted a cumulative meta-analysis and a meta-analysis according to estimated average exposure of each study population.

Results

The meta-analysis resulted in a summary relative risk (RR) for NHL of 0.93 (95% confidence interval 0.83-1.04). The cumulative meta-analysis sugge

SUBMITTER: Catalani S 

PROVIDER: S-EPMC6929467 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature