Old subjects with sepsis in the emergency department: trend analysis of case fatality rate.

ABSTRACT:

Background

The burden of sepsis represents a global health care problem. We aimed to assess the case fatality rate (CFR) and its predictors in subjects with sepsis admitted to a general Italian hospital from 2009 to 2016, stratified by risk score.

Methods

We performed a retrospective analysis of all sepsis-related hospitalizations after Emergency Department (ED) visit in a public Italian hospital in an 8-year period. A risk score to predict CFR was computed by logistic regression analysis of selected variables in a training set (2009-2012), and then confirmed in the whole study population. A trend analysis of CFR during the study period was performed dividing patient as high-risk (upper tertile of risk score) or low-risk.

Results

Two thousand four hundred ninety-two s

SUBMITTER: Fabbri A 

PROVIDER: S-EPMC6929475 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature