Predictive Modelling of Lung Function using Emphysematous Density Distribution.

ABSTRACT: Target lung tissue selection remains a challenging task to perform for treating severe emphysema with lung volume reduction (LVR). In order to target the treatment candidate, the percentage of low attenuation volume (LAV%) representing the proportion of emphysema volume to whole lung volume is measured using computed tomography (CT) images. Although LAV% have shown to have a correlation with lung function in patients with chronic obstructive pulmonary disease (COPD), similar measurements of LAV% in whole lung or lobes may have large variations in lung function due to emphysema heterogeneity. The functional information of regional emphysema destruction is required for supporting the choice of optimal target. The purpose of this study is to develop an emphysema heterogeneity descriptor for t

SUBMITTER: Lor KL 

PROVIDER: S-EPMC6930211 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature