Clinical characteristics and leptomeningeal collateral status in pediatric and adult patients with ischemic moyamoya disease.

ABSTRACT:

Aim

Previous studies have found significant differences in clinical characteristics between pediatric and adult moyamoya disease (MMD) patients, but few studies have focused on the factors underlying these differences. We aimed to investigate the differences in leptomeningeal collateral (LMC) status between pediatric and adult MMD patients and to analyze the effects of LMCs on clinical characteristics and therapeutic prognosis.

Methods

We retrospectively analyzed 214 MMD patients from January 2014 to January 2016. Clinical characteristics and LMC status were compared between the pediatric and adult patients. LMC status was graded as good or poor depending on the retrograde flow from the posterior cerebral artery (PCA) on digital subtraction angiography (DSA).

Results

SUBMITTER: Liu ZW 

PROVIDER: S-EPMC6930821 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature