Multilead template-derived residua of surface ECGS for quantitative assessment of arrhythmia risk.

ABSTRACT:

Background

Contemporary electrocardiographic (ECG) markers including ventricular ectopy and arrhythmias have not proved reliable in risk assessment for life-threatening arrhythmias.

Methods

We developed the "Multilead ECG Template-Derived Residua" approach to remove intrinsic morphologic differences and allow calculation of pathologic ECG heterogeneities among spatially separated leads. Prediction by R-wave and T-wave heterogeneity (RWH, TWH) analysis was tested in simulated and clinical ECGs.

Results

An enabling description of the Residua algorithm is provided. Simulated ECGs with but not without Residua produced a linear relationship (correlation coefficient r(2) = 0.999) between input and output RWH and TWH values. In heart failure patients, Residua disclosed a mar

SUBMITTER: Nearing BD 

PROVIDER: S-EPMC6931747 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature