Andersen syndrome: the newest variant of the hereditary-familial long QT syndrome.

ABSTRACT: Andersen's Syndrome is a rare disease, hereditary with autosomal dominant transmission, of the ion channels of the sarcolemmal membranes of the cardiac and skeletal muscles (channelopathy), which affects chromosome 17 of the KCNJ2 gene, responsible for encoding the outward potassium delayed rectifier current KIR2.1, resulting in a loss or suppression of the function of this channel.

SUBMITTER: Ricardo Perez Riera A 

PROVIDER: S-EPMC6932481 | biostudies-literature | 2004 Apr

REPOSITORIES: biostudies-literature