Quantitative implications of the updated EARL 2019 PET-CT performance standards.

ABSTRACT:

Purpose

Recently, updated EARL specifications (EARL2) have been developed and announced. This study aims at investigating the impact of the EARL2 specifications on the quantitative reads of clinical PET-CT studies and testing a method to enable the use of the EARL2 standards whilst still generating quantitative reads compliant with current EARL standards (EARL1).

Methods

Thirteen non-small cell lung cancer (NSCLC) and seventeen lymphoma PET-CT studies were used to derive four image datasets-the first dataset complying with EARL1 specifications and the second reconstructed using parameters as described in EARL2. For the third (EARL2F6) and fourth (EARL2F7) dataset in EARL2, respectively, 6 mm and 7 mm Gaussian post-filtering was applied. We compared the results of quantitativ

SUBMITTER: Kaalep A 

PROVIDER: S-EPMC6933045 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature