Development and external validation of a dynamic prognostic nomogram for primary extremity soft tissue sarcoma survivors.

ABSTRACT:

Background

Prognostic nomograms for patients with extremity soft tissue sarcoma (eSTS) typically predict survival or the occurrence of local recurrence or distant metastasis at time of surgery. Our aim was to develop and externally validate a dynamic prognostic nomogram for overall survival in eSTS survivors for use during follow-up.

Methods

All primary eSTS patients operated with curative intent between 1994 and 2013 at three European and one Canadian sarcoma centers formed the development cohort. Patients with Fédération Française des Centres de Lutte Contre le Cancer (FNCLCC) grade II and grade III eSTS operated between 2000 and 2016 at seven other European reference centers formed the external validation cohort. We used a landmark analysis approach and a multivariable Co

SUBMITTER: Callegaro D 

PROVIDER: S-EPMC6933187 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature