Comparative metabolome analysis of serum changes in sheep under overgrazing or light grazing conditions.

ABSTRACT: BACKGROUND:Overgrazing is a primary contributor to severe reduction in forage quality and production in Inner Mongolia, leading to extensive ecosystem degradation, sheep health impairment and growth performance reduction. Further studies to identify serum biomarkers that reflect changes in sheep health and nutritional status following overgrazing would be beneficial. We hereby hypothesize that reduced sheep growth performance under overgrazing conditions would be associated with metabolic and immune response alterations. This study used an untargeted metabolomics analysis by conducting ultra-high-performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF/MS) of sheep serum under overgrazing and light grazing conditions to identify metabolic dis

SUBMITTER: Zhang J 

PROVIDER: S-EPMC6933664 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature