Network analysis exposes core functions in major lifestyles of fungal and oomycete plant pathogens.

ABSTRACT: BACKGROUND:Genomic studies demonstrate that components of virulence mechanisms in filamentous eukaryotic pathogens (FEPs, fungi and oomycetes) of plants are often highly conserved, or found in gene families that include secreted hydrolytic enzymes (e.g., cellulases and proteases) and secondary metabolites (e.g., toxins), central to the pathogenicity process. However, very few large-scale genomic comparisons have utilized complete proteomes from dozens of FEPs to reveal lifestyle-associated virulence mechanisms. Providing a powerful means for exploration, and the discovery of trends in large-scale datasets, network analysis has been used to identify core functions of the primordial cyanobacteria, and ancient evolutionary signatures in oxidoreductases. RESULTS:We used a sequence-similarity n

SUBMITTER: Pandaranayaka EP 

PROVIDER: S-EPMC6933724 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature