Electrokinetic Mixing for Improving the Kinetics of an HbA1c Immunoassay.

ABSTRACT: The efficiency of the diagnostic platforms utilizing ELISA technique or immunoassays depends highly on incubation times of the recognition elements or signaling molecules and volume of the patient samples. In conventional immunoassays, long incubation times and excess amounts of the recognition and signaling molecules are used. The technology proposed here uses electrokinetic mixing of the reagents involved in a sandwich immunoassay based diagnostic assay in electrode-enabled microwell plates in such a way that the incubation times and volumes can be reduced substantially. The integration of the electrodes at the bottom of the conventional microwell plates ensures that the motions of the liquid flows in the wells can be controlled through the application of high frequency AC current along

SUBMITTER: Yasun E 

PROVIDER: S-EPMC6934526 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature