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Performance and inter-observer variability of prostate MRI (PI-RADS version 2) outside high-volume centres.


ABSTRACT: Objective: Despite the growing trend to embrace pre-biopsy MRI in the diagnostic pathway for prostate cancer (PC), its performance and inter-observer variability outside high-volume centres remains unknown. This study aims to evaluate sensitivity of and variability between readers of prostate MRI outside specialized units with radical prostatectomy (RP) specimen as the reference standard.Materials and methods: Retrospective study comprising a consecutive cohort of all 97 men who underwent MRI and subsequent RP between January 2012 and December 2014 at a private hospital in Sweden. Three readers, blinded to clinical data, reviewed all images (including 11 extra prostate MRI to reduce bias). A tumour was considered detected if the overall PI-RADS v2 score was 3-5 and there was

SUBMITTER: Kohestani K 

PROVIDER: S-EPMC6935323 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature