Milk Products in the Treatment of Hypophosphatemic Rickets: A Pilot Study.

ABSTRACT:

Background

Standard treatment of hypophosphatemic rickets (HR) is oral phosphate tablets plus vitamin D. Due to the rapid absorption of phosphate tablets, frequent daily doses are necessary, which is cumbersome and may cause fluctuations in plasma phosphate and risk of secondary hyperparathyroidism. It was hypothesized that phosphate from milk or cheese is less rapidly absorbed, and reduces fluctuations in plasma phosphate.

Objectives

The current randomized, multiple crossover study aimed at investigating if an equivalent phosphate dose given as milk or cheese is comparable to phosphate tablets in patients with HR.

Methods

Seven females with HR were included. They went through three different four-day treatment sessions of either oral phosphate tablets consisting of 8

SUBMITTER: Jorgensen CS 

PROVIDER: S-EPMC6935710 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature