Comparative Genomics Reveals Accelerated Evolution of Fright Reaction Genes in Ostariophysan Fishes.

ABSTRACT: The ostariophysian fishes are the most species-rich clade in freshwaters. This diversification has been suggested to be associated with the fright reaction presented in most ostariophysians. However, the genetic forces that underlie fright reaction remains poorly understood. In the present study, through integrating behavioral, physiological, transcriptomic, and evolutionary genomic analyses, we found that the fright reaction has a broad impact on zebrafish at multiple levels, including changes in swimming behaviors, cortisol levels, and gene expression patterns. In total, 1,555 and 1,599 differentially expressed genes were identified in olfactory mucosae and brain of zebrafish, respectively, with a greater number upregulated after the fright reaction. Functional annotation showed that res

SUBMITTER: Yang L 

PROVIDER: S-EPMC6936194 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature