Cerebral cortical folding, parcellation, and connectivity in humans, nonhuman primates, and mice.

ABSTRACT: Advances in neuroimaging and neuroanatomy have yielded major insights concerning fundamental principles of cortical organization and evolution, thus speaking to how well different species serve as models for human brain function in health and disease. Here, we focus on cortical folding, parcellation, and connectivity in mice, marmosets, macaques, and humans. Cortical folding patterns vary dramatically across species, and individual variability in cortical folding increases with cortical surface area. Such issues are best analyzed using surface-based approaches that respect the topology of the cortical sheet. Many aspects of cortical organization can be revealed using 1 type of information (modality) at a time, such as maps of cortical myelin content. However, accurate delineation of the en

SUBMITTER: Van Essen DC 

PROVIDER: S-EPMC6936571 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature