Sleep-disordered breathing is associated with brain vascular reactivity in spinal cord injury.

ABSTRACT: Objective: To determine the population-level odds of individuals with spinal cord injury (SCI) experiencing fatigue and sleep apnea, to elucidate relationships with level and severity of injury, and to examine associations with abnormal cerebrovascular responsiveness.

Methods: We used population-level data, meta-analyses, and primary physiologic assessments to provide a large-scale integrated assessment of sleep-related complications after SCI. Population-level and meta-analyses included more than 60,000 able-bodied individuals and more than 1,800 individuals with SCI. Physiologic assessments were completed on a homogenous sample of individuals with cervical SCI and matched controls. We examined the prevalence of (1) self-reported chronic fatigue, (2) clinically identi

SUBMITTER: Squair JW 

PROVIDER: S-EPMC6937492 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature