Profile of and risk factors for poststroke cognitive impairment in diverse ethnoregional groups.

ABSTRACT:

Objective

To address the variability in prevalence estimates and inconsistencies in potential risk factors for poststroke cognitive impairment (PSCI) using a standardized approach and individual participant data (IPD) from international cohorts in the Stroke and Cognition Consortium (STROKOG) consortium.

Methods

We harmonized data from 13 studies based in 8 countries. Neuropsychological test scores 2 to 6 months after stroke or TIA and appropriate normative data were used to calculate standardized cognitive domain scores. Domain-specific impairment was based on percentile cutoffs from normative groups, and associations between domain scores and risk factors were examined with 1-stage IPD meta-analysis.

Results

In a combined sample of 3,146 participants admitted to hos

SUBMITTER: Lo JW 

PROVIDER: S-EPMC6937495 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature