The chick pallium displays divergent expression patterns of chick orthologues of mammalian neocortical deep layer-specific genes.

ABSTRACT: The avian pallium is organised into clusters of neurons and does not have layered structures such as those seen in the mammalian neocortex. The evolutionary relationship between sub-regions of avian pallium and layers of mammalian neocortex remains unclear. One hypothesis, based on the similarities in neural connections of the motor output neurons that project to sub-pallial targets, proposed the cell-type homology between brainstem projection neurons in neocortex layers 5 or 6 (L5/6) and those in the avian arcopallium. Recent studies have suggested that gene expression patterns are associated with neural connection patterns, which supports the cell-type homology hypothesis. However, a limited number of genes were used in these studies. Here, we showed that chick orthologues of mammalian L

SUBMITTER: Fujita T 

PROVIDER: S-EPMC6938507 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature