Atypical processing of social anticipation and feedback in borderline personality disorder.

ABSTRACT:

Background-

Borderline personality disorder (BPD) is characterized by maladaptive social functioning, and widespread negativity biases. The neural underpinnings of these impairments remain elusive. We thus tested whether BPD patients show atypical neural activity when processing social (compared to non-social) anticipation, feedback, and particularly, how they relate to each other.

Methods-

We acquired functional MRI data from 21 BPD women and 24 matched healthy controls (HCs) while they performed a task in which cues and feedbacks were either social (neutral faces for cues; happy or angry faces for positive and negative feedbacks, respectively) or non-social (dollar sign; winning or losing money for positive and negative feedbacks, respectively). This task allowed for the a

SUBMITTER: Doell KC 

PROVIDER: S-EPMC6938803 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature