Abnormal expression of rno_circRNA_014900 and rno_circRNA_005442 induced by ketamine in the rat hippocampus.
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ABSTRACT:
SUBMITTER: Mao J
PROVIDER: S-EPMC6939336 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
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Abnormal expression of rno_circRNA_014900 and rno_circRNA_005442 induced by ketamine in the rat hippocampus.
Mao Jing J Li Tianmei T Fan Di D Zhou Hongli H Feng Jianguo J Liu Li L Zhang Chunxiang C Wang Xiaobin X
BMC psychiatry 20200102 1
<h4>Background</h4>Recent studies have shown that circular RNA (circRNA) is rich in microRNA (miRNA) binding sites. We have previously demonstrated that the antidepressant effect of ketamine is related to the abnormal expression of various miRNAs in the brain. This study determined the expression profile of circRNAs in the hippocampus of rats treated with ketamine.<h4>Methods</h4>The aberrantly expressed circRNAs in rat hippocampus after ketamine injection were analyzed by microarray chip, and w ...[more]
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