Impact of Aortic Atherosclerosis Burden on Outcomes of Surgical Aortic Valve Replacement.

ABSTRACT:

Background

Epiaortic ultrasound detects and localizes ascending aortic atherosclerosis. In this analysis we investigated the association between epiaortic ultrasound-based atheroma grade during surgical aortic valve replacement (SAVR) and perioperative adverse outcomes.

Methods

SAVR patients in a randomized trial of 2 embolic protection devices underwent a protocol-defined 5-view epiaortic ultrasound read at a core laboratory. Aortic atherosclerosis was quantified with the Katz atheroma grade, and patients were categorized as mild (grade I-II) or moderate/severe (grade III-V). Multivariable logistic regression was used to estimate associations between atheroma grade and adverse outcomes, including death, clinically apparent stroke, cerebral infarction on diffusion-weighted m

SUBMITTER: Iribarne A 

PROVIDER: S-EPMC6939455 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature