Whipple's endocarditis: a case report of a blood culture-negative endocarditis.

ABSTRACT:

Background

Whipple's disease is caused by Tropheryma whipplei and causes a self-limiting gastrointestinal infection. The majority of the population is an asymptomatic carrier, however, in some patients, it causes an invasive infection with for example arthritis, endocarditis, or involvement of the eyes.

Case summary

This case describes a man with long-lasting complaints of progressive dyspnoea caused by heart failure due to total destruction of the aortic and mitral valve as a result of T. whipplei endocarditis, diagnosed with serum polymerase chain reaction. The patient was treated with ceftriaxone and prolonged co-trimoxazole therapy and surgical replacement of the aortic and mitral valve. He was discharged to a rehabilitation centre.

Discussion

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SUBMITTER: Scheurwater MA 

PROVIDER: S-EPMC6939820 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature