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Aspirin use and pancreatic cancer risk: A systematic review of observational studies.


ABSTRACT:

Objectives

Although there is evidence that aspirin might be able to prevent pancreatic cancer, the findings have been inconsistent. In this paper, we conducted a meta-analysis of observational studies to examine the relationship between aspirin use and the risk of pancreatic cancer.

Methods

We identified potential studies by searching the MEDLINE, EMBASE, and Wangfang (Chinese database) database (from 1967 to March 2017) and by reviewing the bibliography of relevant publications. Random effects model was used to calculate odds ratio (OR) and 95% confidence interval. The Cochran Q statistic (significance level at P < .1) was used to assess heterogeneity in this study. The author adopted weighted regression method of Egger to assessed publication bias.

Results

A total o

SUBMITTER: Sun J 

PROVIDER: S-EPMC6940047 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature