Active Cancer and Elevated D-Dimer Are Risk Factors for In-Hospital Ischemic Stroke.

ABSTRACT:

Background and purpose

Little attention has been paid to the pathogenesis of in-hospital stroke, despite poor outcomes and a longer time from stroke onset to treatment. We studied the pathophysiology and biomarkers for detecting patients who progress to in-hospital ischemic stroke (IHS).

Methods

Seventy-nine patients with IHS were sequentially recruited in the period 2011-2017. Their characteristics, care, and outcomes were compared with 933 patients who had an out-of-hospital ischemic stroke (OHS) using a prospectively collected database of the Tokushima University Stroke Registry.

Results

Active cancer and coronary artery disease were more prevalent in patients with IHS than in those with OHS (53.2 and 27.8% vs. 2.0 and 10.9%, respectively; p < 0.001), the median on

SUBMITTER: Yamaguchi I 

PROVIDER: S-EPMC6940458 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature