Association of GST gene polymorphism and noise-induced hearing loss: GST gene polymorphism and NIHL.

ABSTRACT:

Background

It has been proposed that Noise-induced hearing loss is a complex disease that is combination of environmental and genetic factors. There are inconsistent results concerning the association between variation in glutathione S-transferase (GST) genetic polymorphisms (GSTT1 rs1049055 and GSTM1 rs10712361) and susceptibility to Noise-induced hearing loss.

Objective

This study was designed to assess the association between GST gene polymorphism and Noise-induced hearing loss among noise-exposed workers. Methods: In a case-control study, male workers from tile and ceramic factories were selected randomly. Subjects were classified into two groups according to the result of audiometry: 73 subjects showed Noise-induced hearing loss which

SUBMITTER: Loukzadeh Z 

PROVIDER: S-EPMC6940572 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature