A detailed in silico analysis of secondary metabolite biosynthesis clusters in the genome of the broad host range plant pathogenic fungus Sclerotinia sclerotiorum.

ABSTRACT:

Background

The broad host range pathogen Sclerotinia sclerotiorum infects over 400 plant species and causes substantial yield losses in crops worldwide. Secondary metabolites are known to play important roles in the virulence of plant pathogens, but little is known about the secondary metabolite repertoire of S. sclerotiorum. In this study, we predicted secondary metabolite biosynthetic gene clusters in the genome of S. sclerotiorum and analysed their expression during infection of Brassica napus using an existing transcriptome data set. We also investigated their sequence diversity among a panel of 25 previously published S. sclerotiorum isolate genomes.

Results

We identified 80 putative secondary metabolite clusters. Over half of the clusters contained at least three trans

SUBMITTER: Graham-Taylor C 

PROVIDER: S-EPMC6941272 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature