Naloxone Dosing After Opioid Overdose in the Era of Illicitly Manufactured Fentanyl.

ABSTRACT:

Introduction

Illicitly manufactured fentanyl (IMF) is responsible for a growing number of deaths. Some case series have suggested that IMF overdoses require significantly higher naloxone doses than heroin overdoses. Our objective was to determine if the naloxone dose required to treat an opioid overdose is associated with the finding of fentanyl, opiates, or both on urine drug screen (UDS).

Methods

A retrospective chart review was conducted at a single emergency department and its affiliated emergency medical services (EMS) agency. The charts of all patients who received naloxone through this EMS from 1/1/2017 to 6/15/2018 were reviewed. The study included patients diagnosed with a non-suicidal opioid overdose whose UDS was positive for opiates, fentanyl, or both. Data colle

SUBMITTER: Carpenter J 

PROVIDER: S-EPMC6942078 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature