Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels.

ABSTRACT:

Background

Inflammatory bowel disease (IBD), is a debilitating group of chronic diseases including Crohn's Disease (CD) and ulcerative colitis (UC), which causes inflammation of the gut and affects millions of people worldwide. At different taxonomic levels, the structure of the gut microbiota is significantly altered in IBD patients compared to that of healthy individuals. However, it is unclear how these IBD-affected bacterial groups are related to other common bacteria in the gut, and how they are connected across different disease conditions at the global scale.

Results

In this study, using faecal samples from patients with IBD, we show through diversity analysis of the microbial community structure based on the 16S rRNA gene that the gut microbiome of IBD patients is le

SUBMITTER: Alam MT 

PROVIDER: S-EPMC6942256 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature