Quantifying the relative impact of contact heterogeneity on MRSA transmission in ICUs - a modelling study.

ABSTRACT: BACKGROUND:An efficient surface cleaning strategy would first target cleaning to surfaces that make large contributions to the risk of infections. METHODS:In this study, we used data from the literature about methicillin-resistant Staphylococcus aureus (MRSA) and developed an ordinary differential equations based mathematical model to quantify the impact of contact heterogeneity on MRSA transmission in a hypothetical 6-bed intensive care unit (ICU). The susceptible patients are divided into two types, these who are cared by the same nurse as the MRSA infected patient (Type 1) and these who are not (Type 2). RESULTS:The results showed that the mean MRSA concentration on three kinds of susceptible patient nearby surfaces was significantly linearly associated with the hand-touch frequency (p 

SUBMITTER: Lei H 

PROVIDER: S-EPMC6942315 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature