MSDB: a comprehensive, annotated database of microsatellites.

ABSTRACT: Microsatellites are short tandem repeats of 1-6 nucleotide motifs, studied for their utility as genome markers and in forensics. Recent evidence points to the role of microsatellites in important regulatory functions, and their length polymorphisms at coding regions are linked to various neurodegenerative disorders in humans. Microsatellites show a taxon-specific enrichment in eukaryotic genomes, and their evolution remains poorly understood. Though other databases of microsatellites exist, they fall short on several fronts. MSDB (MicroSatellite DataBase) is a collection of >4 billion microsatellites from 37 680 genomes presented in a user-friendly web portal for easy, interactive analysis and visualization. This is by far the most comprehensive, annotated, updated database to access and a

SUBMITTER: Avvaru AK 

PROVIDER: S-EPMC6943038 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature