KnockTF: a comprehensive human gene expression profile database with knockdown/knockout of transcription factors.

ABSTRACT: Transcription factors (TFs) and their target genes have important functions in human diseases and biological processes. Gene expression profile analysis before and after knockdown or knockout is one of the most important strategies for obtaining target genes of TFs and exploring TF functions. Human gene expression profile datasets with TF knockdown and knockout are accumulating rapidly. Based on the urgent need to comprehensively and effectively collect and process these data, we developed KnockTF (http://www.licpathway.net/KnockTF/index.html), a comprehensive human gene expression profile database of TF knockdown and knockout. KnockTF provides a number of resources for human gene expression profile datasets associated with TF knockdown and knockout and annotates TFs and their target genes

SUBMITTER: Feng C 

PROVIDER: S-EPMC6943067 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature