Functional Gene Network of Prenyltransferases in Arabidopsis thaliana.

ABSTRACT: Prenyltransferases (PTs) are enzymes that catalyze prenyl chain elongation. Some are highly similar to each other at the amino acid level. Therefore, it is difficult to assign their function based solely on their sequence homology to functional orthologs. Other experiments, such as in vitro enzymatic assay, mutant analysis, and mutant complementation are necessary to assign their precise function. Moreover, subcellular localization can also influence the functionality of the enzymes within the pathway network, because different isoprenoid end products are synthesized in the cytosol, mitochondria, or plastids from prenyl diphosphate (prenyl-PP) substrates. In addition to in vivo functional experiments, in silico approaches, such as co-expression analysis, can provide information about the t

SUBMITTER: Kopcsayova D 

PROVIDER: S-EPMC6943727 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature