Technology-enabled comprehensive characterization of multiple sclerosis in clinical practice.

ABSTRACT:

Background

Objective and longitudinal measurements of disability in patients with multiple sclerosis (MS) are desired in order to monitor disease status and response to disease-modifying and symptomatic therapies. Technology-enabled comprehensive assessment of MS patients, including neuroperformance tests (NPTs), patient-reported outcome measures (PROMs), and MRI, is incorporated into clinical care at our center. The relationships of each NPT with PROMs and MRI measures in a real-world setting are incompletely studied, particularly in larger datasets.

Objectives

To demonstrate the utility of comprehensive neurological assessment and determine the association between NPTs, PROMs, and quantitative MRI measures in a large MS clinical cohort.

Methods

NPTs (processing spee

SUBMITTER: Baldassari LE 

PROVIDER: S-EPMC6943942 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature