Phantom-based image quality assessment of clinical ¹⁸F-FDG protocols in digital PET/CT and comparison to conventional PMT-based PET/CT.

ABSTRACT:

Background

We assessed and compared image quality obtained with clinical ¹⁸F-FDG whole-body oncologic PET protocols used in three different, state-of-the-art digital PET/CT and two conventional PMT-based PET/CT devices. Our goal was to evaluate an  improved trade-off between administered activity (patient dose exposure/signal-to-noise ratio) and acquisition time (patient comfort) while preserving diagnostic information achievable with the recently introduced digital detector technology compared to previous analogue PET technology.

Methods

We performed list-mode (LM) PET acquisitions using a NEMA/IEC NU2 phantom, with activity concentrations of 5 kBq/mL and 25 kBq/mL for the background (9.5 L) and sphere inserts, respectively. For each device, reconstructions were

SUBMITTER: Gnesin S 

PROVIDER: S-EPMC6944719 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature