Is the delivery mode a critical factor for the microbial communities in the meconium?

ABSTRACT:

Background

Mothers are the primary source of bacteria for newborns, but it is unclear whether mother-to-newborn transmission occurs prior to, during or after birth. Similarly, the effect of the delivery mode on neonatal microorganisms has been the focus of controversy.

Methods

Healthy maternal and neonatal pairs that underwent vaginal birth and caesarean section were enrolled in this study. Meconium, placenta, membrane and amniotic fluid samples for newborns and vaginal, rectal and oral samples for mothers were collected. All samples were amplified and sequenced by a 16S rRNA gene primer set targeting bacteria and archaea.

Findings

A total of 550 samples from 36 mother-neonate pairs with vaginal births and 42 mother-neonate pairs with caesarean sections were included

SUBMITTER: Liu CJ 

PROVIDER: S-EPMC6945248 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature