Non-selective beta blocker use is associated with improved short-term survival in patients with cirrhosis referred for liver transplantation.

ABSTRACT: BACKGROUND:Recent evidence cautions against the use of non-selective beta-blockers (NSBB) in patients with refractory ascites or spontaneous bacterial peritonitis while other data suggests a survival benefit in patients with advanced liver disease. The aim of this study was to describe the use and impact of NSBB in patients with cirrhosis referred for liver transplantation. METHODS:A single-center cohort of patients with cirrhosis, who were referred and evaluated for liver transplantation between January and June 2012 were studied for baseline characteristics and clinical outcomes. Patients were grouped according to the use of NSBB at initial evaluation, with the endpoint of 90-day mortality. RESULTS:Sixty-five (38%) of 170 consecutive patients evaluated for liver transplantation were taki

SUBMITTER: Ngwa T 

PROVIDER: S-EPMC6945622 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature