Prediction of pre-eclampsia in nulliparous women using routinely collected maternal characteristics: a model development and validation study.

ABSTRACT:

Background

Guidelines recommend identifying in early pregnancy women at elevated risk of pre-eclampsia. The aim of this study was to develop and validate a pre-eclampsia risk prediction model for nulliparous women attending routine antenatal care "the Western Sydney (WS) model"; and to compare its performance with the National Institute of Health and Care Excellence (NICE) risk factor-list approach for classifying women as high-risk.

Methods

This retrospective cohort study included all nulliparous women who gave birth in three public hospitals in the Western-Sydney-Local-Health-District, Australia 2011-2014. Using births from 2011 to 2012, multivariable logistic regression incorporated established maternal risk factors to develop and internally validate the WS model. The WS

SUBMITTER: Al-Rubaie ZTA 

PROVIDER: S-EPMC6945640 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature