Circadian disruption of core body temperature in trauma patients: a single-center retrospective observational study.

ABSTRACT:

Background

Circadian clock alterations were poorly reported in trauma patients, although they have a critical role in human physiology. Core body temperature is a clinical variable regulated by the circadian clock. Our objective was to identify the circadian temperature disruption in trauma patients and to determine whether these disruptions were associated with the 28-day mortality rate.

Methods

A retrospective and observational single-center cohort study was conducted. All adult severe trauma patients admitted to the intensive care unit of Aix Marseille University, North Hospital, from November 2013 to February 2018, were evaluated. The variations of core body temperature for each patient were analyzed between days 2 and 3 after intensive care unit admission. Core body tem

SUBMITTER: Culver A 

PROVIDER: S-EPMC6945723 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature