Proton pump inhibitors and hypomagnesemia: A meta-analysis of observational studies.

ABSTRACT:

Background

Previous meta-analyses have suggested that there might be an association between the use of proton pump inhibitors (PPIs) and the development of hypomagnesemia, although the conclusions were no definitive.

Methods

To provide an update on this topic, we performed a meta-analysis of all observational studies that examined the association between the use of PPIs and the development of hypomagnesemia. A literature search was conducted in MEDLINE, Scopus and Cochrane Central Register of Controlled Trials (January 1970 to June 2018) to identify observational studies that examined the association between the use of PPIs and the incidence and prevalence of hypomagnesemia.

Study eligibility criteria

In the absence of randomized controlled trials, we focused primaril

SUBMITTER: Srinutta T 

PROVIDER: S-EPMC6946416 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature