The Influence of Histologic Inflammation on the Improvement of Liver Stiffness Values Over 1 and 3 Years.

ABSTRACT: Transient elastography is now an indispensable tool for estimating liver fibrosis. Although many clinical factors other than fibrosis itself are known to affect liver stiffness (LS) values, it is still not yet clear what factors are related to improving LS values. The aim of this study was to find out how baseline histologic inflammation influences LS values and how much this inflammation affects improvement in LS values over time, regardless of actual fibrosis content. This retrospective study included 678 consecutive patients who underwent liver biopsy and sequential LS assessment from 2006 to 2015 at six tertiary hospitals in Korea. Linear regression analysis was used to evaluate how improvement of LS value can be associated with other factors besides fibrosis content. Basal LS values i

SUBMITTER: Yoo JJ 

PROVIDER: S-EPMC6947085 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature