Phylogeny, Resistome, and Virulome of Escherichia coli Causing Biliary Tract Infections.

ABSTRACT: Escherichia coli is the most frequent Gram-negative bacilli involved in intra-abdominal infections. However, despite high mortality rates associated with biliary tract infections due to E. coli, there is no study focusing on this pathogen. In this study, we have characterized a group of 15 E. coli isolates obtained from 12 patients with biliary tract infections. Demographic and clinical data of the patients were recovered. Phylogeny, resistome, and virulome analysis through whole genome sequencing and biofilm formation were investigated. Among the 15 E. coli isolates, no predominant sequence type (ST) was identified, although 3 of them belonged to unknown STs (20%). Resistance to ampicillin, amoxicillin/clavulanic acid, cotrimoxazole, and quinolones was more pre

SUBMITTER: Rodriguez-Villodres A 

PROVIDER: S-EPMC6947626 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature