A clinical method for estimating the modulus of elasticity of the human cornea in vivo.

ABSTRACT:

Background

To develop a method, using current clinical instrumentation, to estimate the Young's modulus of the human cornea in vivo.

Methods

Central corneal curvature (CCC), central corneal thickness(CCT), intraocular pressure (IOP) was measured with the Goldmann tonometer (IOPG) and the Pascal Dynamic Corneal Tonometer(PDCT) in one eye of 100 normal young human subjects (21.07 ± 2.94 years) in vivo. The Orssengo and Pye algorithm was used to calculate the Young's modulus of the corneas of these subjects.

Results

The Young's modulus(E) of the corneas of the subjects using the PDCT and IOPG results (Ecalc) was 0.25 ± 0.10MPa, and without the PDCT results (Eiopg) was 0.29 ± 0.06MPa. The difference in these results is due to the difference in tonometry results between th

SUBMITTER: Pye DC 

PROVIDER: S-EPMC6948750 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature