Dataset Information
An In silico Approach to Identify High Affinity Small Molecule
Ontology highlight
ABSTRACT:
SUBMITTER: Patidar K
PROVIDER: S-EPMC6948900 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Publications
An In silico Approach to Identify High Affinity Small Molecule Targeting m-TOR Inhibitors for the Clinical Treatment of Breast Cancer
Asian Pacific journal of cancer prevention : APJCP 20190429 4
Breast cancer is the most frequent malignancy among women. It is a heterogeneous disease with different subtypes defined by its hormone receptor. A hormone receptor is mainly concerned with the progression of the PI3K/AKT/ mTOR pathway which is often dysregulated in breast cancer. This is a major signaling pathway that controls the activities such as cell growth, cell division, and cell proliferation. The present study aims to suppress mTOR protein by its various inhibitors and to select one wit ...[more]
