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Vitamin D-Binding protein Gene Polymorphism Predicts

ABSTRACT: Background: Vitamin D deficiency is related to poor clinical outcomes in patients with chronic hepatitis B virus

SUBMITTER: Thanapirom K 

PROVIDER: S-EPMC6948901 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Background: Vitamin D deficiency is related to poor clinical outcomes in patients with chronic hepatitis B virus (HBV) infection. Methods: We aimed to investigate the association between the genetic variants in the vitamin D metabolic pathway and the response to pegylated interferon (Peg-IFN) therapy in patients with HBeAg-negative chronic HBV infection. One hundred seven patients treated with Peg-IFN for 48 weeks were selected from 13 specialty hospitals. Eight genotypes of vitamin D cascade ge  ...[more]

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