Preoperative Delays in the Treatment of DCIS and the Associated Incidence of Invasive Breast Cancer.

ABSTRACT:

Background

Although treatment delays have been associated with survival impairment for invasive breast cancer, this has not been thoroughly investigated for ductal carcinoma in situ (DCIS). With trials underway to assess whether DCIS can remain unresected, this study was performed to determine whether longer times to surgery are associated with survival impairment or increased invasion.

Methods

A population-based study of prospectively collected national data derived from women with a clinical diagnosis of DCIS between 2004 and 2014 was conducted using the National Cancer Database. Overall survival (OS) and presence of invasion were assessed as functions of time by evaluating five intervals (≤ 30, 31-60, 61-90, 91-120, 121-365 days) between diagnosis and surgery. Subset anal

SUBMITTER: Ward WH 

PROVIDER: S-EPMC6949196 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature