Early recovery in the first 24 months of treatment in first-episode schizophrenia-spectrum disorders.

ABSTRACT: Studies assessing the treatment outcomes in first-episode schizophrenia have reported mixed results. While symptom improvement is frequently robust, when other domains are considered outcomes are generally poorer. We explored response trajectories, rates and predictors of recovery in the domains of core psychopathology, clinician-rated social and occupational functioning and patient-rated quality of life over 24 months of treatment in 98 patients with first-episode schizophrenia spectrum disorders who were treated with a long-acting antipsychotic medication. There was robust improvement in core psychopathology (effect size d = 3.36) and functionality (d = 1.78), with most improvement occurring within the first six months of treatment. In contrast, improvement in subjective quality of life

SUBMITTER: Phahladira L 

PROVIDER: S-EPMC6949247 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature