A comprehensive global perspective on phylogenomics and evolutionary dynamics of Small ruminant morbillivirus.

ABSTRACT: A string of complete genome sequences of Small ruminant morbillivirus (SRMV) have been reported from different parts of the globe including Asia, Africa and the Middle East. Despite individual genome sequence-based analysis, there is a paucity of comparative genomic and evolutionary analysis to provide overarching and comprehensive evolutionary insights. Therefore, we first enriched the existing database of complete genome sequences of SRMVs with Pakistan-originated strains and then explored overall nucleotide diversity, genomic and residue characteristics, and deduced an evolutionary relationship among strains representing a diverse geographical region worldwide. The average number of pairwise nucleotide differences among the whole genomes was found to be 788.690 with a diversity in nucle

SUBMITTER: Shabbir MZ 

PROVIDER: S-EPMC6949297 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature