Bovine Foamy Virus: Shared and Unique Molecular Features In Vitro and In Vivo.

ABSTRACT: The retroviral subfamily of Spumaretrovirinae consists of five genera of foamy (spuma) viruses (FVs) that are endemic in some mammalian hosts [1]. Closely related species may be susceptible to the same or highly related FVs. FVs are not known to induce overt disease and thus do not pose medical problems to humans and livestock or companion animals. A robust lab animal model is not available or is a lab animal a natural host of a FV. Due to this, research is limited and often focused on the simian FVs with their well-established zoonotic potential. The authors of this review and their groups have conducted several studies on bovine FV (BFV) in the past with the intention of (i) exploring the risk of zoonotic infection via beef and raw cattle products, (ii) studying a co-factorial role of BF

SUBMITTER: Materniak-Kornas M 

PROVIDER: S-EPMC6950176 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature